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lacto bacto
menu
more concerns with nanoparticles in foods
are fungi growing on your wallpaper?
common chemicals linked to chronic diseases
red meat allergies from a tick bite?
drinking coffee may reduce risk of death
is olive oil good for the aging brain?
lose weight if you can’t smell your food?
do probiotics treat depression or not?
did you have some chocolate today?
it is normal to have archaea on our skin
H2
health, microbes, and more
H3
post navigation
categories
archives
H4
H5
H6
strong
nanoparticles in foods
titanium dioxide
silicon dioxide
 zinc oxide
titanium dioxide
e171
there may be health effects from the nanoparticles in our food
individuals with inflammatory intestinal conditions such as intestinal bowel disease (colitis and crohn's disease) might have negative health effects 
worsen intestinal inflammation
nanoparticles accumulated in spleens of mice
levels of titanium were increased in the blood of patients with active colitis
titanium dioxide nanoparticles can exacerbate colitis
titanium dioxide
nanoparticles
when intestinal cells absorb titanium dioxide particles, this leads to increased inflammation and damage to the intestinal mucosa in mice with colitis.
patients with colitis should avoid food containing titanium dioxide particles
titanium dioxide nanoparticles can intensify the inflammatory reaction in the bodies of patients with inflammatory intestinal diseases.
no restrictions on its use in the food industry
nlrp3 inflammasome
part of the non-specific immune system, which detects danger signals and then triggers inflammation
nlrp3 can be activated by small inorganic particles
titanium dioxide can penetrate human intestinal epithelial cells and macrophages and accumulate there
patients with ulcerative colitis, whose intestinal barrier is disrupted, have an increased concentration of titanium dioxide in their blood
the particles activated the nlrp3 complex, which led to strong intestinal inflammation and greater damage to the intestinal mucosa in the mice
accumulated in the animals' spleens
based on our results,"
"patients with an intestinal barrier dysfunction as found in colitis should abstain from foods containing titanium dioxide
wallpaper could have fungi (mold) living on it
fungi can release toxins (mycotoxins) that can pollute the air and sicken people when people inhale the toxins
sick building syndrome
why does fungi grow on some wallpaper?
high humidity in the home
water damage
how do the mycotoxins get into the air and move around inside the home?
we normally
breathe in fungi and bacteria
, but inhaling an overload of mycotoxins from moldy wallpaper can sicken a person
fungal toxins from wallpaper source of illness says new research
there are several toxins from fungi that could be released into the air indoors and the source could be fungi living in the wall papers
ordinary fungi that live with the household wallpaper are basically of three types
they can grow and eventually spread to the air
the toxins released from the fungi are called mycotoxins
sick building syndrome
these mycotoxins are released from moldy material of growth of the fungi.
inhaled by the inhabitants of the home
penicillium brevicompactum, aspergillus versicolor and stachybotrys chartarum. a piece of wallpaper was found to be contaminated with these three fungi
on analysis of the indoor air the researchers found that the small particles of dust floating around in the house which could then be inhaled easily, contained toxins from these fungi
phthalates
chemicals used widely in common consumer products
endocrine disruptors
linked to a number of health problems
the higher the level of phthalates, the higher the rate of cardiovascular disease, type-2 diabetes, and hypertension
higher levels of chronic low-grade inflammatory biomarkers
phthalates, which are measured in the urine,  were detected in 99.96% of the 1504 men
everyday chemicals linked to chronic disease in men
chemicals found in everyday plastics materials are linked to cardiovascular disease, type-2 diabetes and high blood pressure in men
association between chronic diseases among men
chemicals known as
phthalates
phthalates
phthalates were detected in urine samples of 99.6% of those aged 35 and ove
prevalence of cardiovascular disease, type-2 diabetes and high blood pressure increased among those men with higher total phthalate levels
the chemicals impact on the human endocrine system , which controls hormone release that regulate the body's growth, metabolism, and sexual development and function. 
higher phthalate levels were associated with increased levels of a range of inflammatory biomarkers in the body
age and western diets are directly associated with higher concentrations of phthalates
although the studies were conducted in men, the findings are also likely to be relevant to women
  red meat allergies from a lone star tick bite?
eat some red meat (beef, pork, or venison) and a few hours later have severe allergy symptoms
lone star tick
alpha-gal allergy syndrome 
alpha-gal
oh, lovely: the tick that gives people meat allergies is spreading
in the last decade and a half, thousands of previously protein-loving americans have developed a dangerous allergy to meat.
the lone star tick
red meat
galactose-alpha-1,3-galactose, or alpha-gal
suddenly develop a life-threatening allergy to that pesky sugar molecule after a tick bite.
, one bite from the lone star tick—which gets its name from the texas-shaped splash of white on its back—is enough to reprogram your immune system to forever reject even the smallest nibble of perfectly crisped bacon
southeastern united states
it’s started to spread
duluth, minnesota, hanover, new hampshire, and the eastern tip of long island
tick bites led to a 20-fold increase in alpha-gal antibodies
something in the tick’s saliva hijacks humans’ immune systems, red-flagging alpha-gal, and triggering the massive release of histamines whenever red meat is consumed
alpha-gal syndrome seems to be the only allergy that affects all people, regardless of genetic makeup.
health benefits associated with drinking coffee daily - this time "reduced risk of death" in 2 studies, and in one study a reduced risk of gallbladder cancer
coffee
both decaffeinated and regular coffee seem beneficial, and it doesn't matter how it is prepared
higher consumption of coffee was associated with a lower risk of death from heart disease, cancer, stroke, diabetes, and kidney disease in african americans, japanese americans, latinos, and whites
coffee drinking was associated with lower risk for death from "all causes", especially from circulatory diseases and diseases related to the digestive tract
the one negative result from drinking more than 3 cups of coffee daily was an increase in risk for ovarian cancer mortality in women
drink coffee? it won’t hurt you, and may reduce your risk of an early death
a couple of massive new studies that looked at hundreds of thousands of people for about 16 years finds that a few cups of coffee a day won’t hurt you and could lower your risk of dying prematurely
521,000 adults from 10 european countries who self-reported their coffee consumption over an average of 16 years
highest 25 percent of coffee consumers had a lower risk of death due to any cause compared to non-coffee drinkers
reduced risk of early death by diseases related to the digestive and circulatory systems
higher coffee consumption and lower risk of early death by lung cancer in men
completed suicides were lower for coffee drinkers, but only in men
180,000 people tracked for an average of 16 years
drinking one to six cups of coffee per week led to a decreased risk of early death
their findings proved consistent for coffee drinkers across racial and ethnic groups
coffee consumption may be linked a lower risk of early death for people with heart disease, cancer, chronic lower respiratory disease, stroke, and kidney disease.
coffee consumption and risk of gallbladder cancer in a prospective study
coffee consumption may reduce the risk of gallstone disease
which is strongly associated with increased risk of gallbladder cancer
coffee consumption was observed to be associated with a reduced risk of gallbladder cancer
  
extra virgin olive oil (evoo)
mediterranean diet
olive oil in the mediterranean diet probably promotes healthy brain aging
they are taking findings from their study done on mice and hypothesizing that this is what is also going on in humans.
enjoy olive oil in your diet - looks like it will benefit your health in a number of ways
olive oil key ingredient in alzheimer's prevention?
extra-virgin olive oil (evoo)
protect memory and learning ability and reduces the formation of beta amyloid (aβ) plaques and neurofibrillary tangles in the brain
it is the olive oil component of the mediterranean diet that likely promotes healthy brain aging
absolutely encourage people to consume greater amounts of evoo
mice fed the evoo-enriched diet performed significantly better at both 9 and 12 months on tests designed to assess working memory, spatial memory, and learning abilities compared with mice fed regular chow
significant reduction in the amount of aβ peptides deposited in the brains of the evoo-treated animals
a significant reduction in the phosphorylated forms of tau in mice fed the evoo-enriched chow
improvements in cognitive performance and brain pathology that were observed in evoo-treated mice
they found greater preservation in the integrity of the synapses between neurons in evoo-fed mice compared with controls
a dramatic increase in nerve cell autophagy activation in brain cells from the evoo-fed animals
autophagy
autophagy digests and gets rid of both amyloid plaques and phosphorylated tau
 
the results of this study done in mice are that actually smelling the food one eats results in weight gain , and not being able to smell the food results in weight loss - even if both groups eat the same amount of food.
supersmellers
 
odor of what we eat
how the body deals with calories
a link between smell and metabolism
smelling your food makes you fat
obese mice who lost their sense of smell also lost weight. 
these slimmed-down but smell-deficient mice ate the same amount of fatty food as mice that retained their sense of smell and ballooned to twice their normal weight
super-smellers—got even fatter on a high-fat diet than did mice with normal smell.
the findings suggest that the odor of what we eat may play an important role in how the body deals with calories
key connection between the olfactory or smell system and regions of the brain that regulate metabolism, in particular the hypothalamus
sensory systems play a role in metabolism
beige fat cells
brown fat cells
some turned almost all of their beige fat into brown fat, becoming lean, mean burning machines
white fat cells
noradrenaline
in humans, such a sustained rise in this hormone could lead to a heart attack
in both cases, the smell-deficient mice ate as much of the high-fat food as did the mice that could still smell.
mice that were already obese lost weight after their smell was knocked out, slimming down to the size of normal mice while still eating a high-fat diet.
supersmellers
they gained more weight on a standard diet than did normal mice
 could probiotics be used to treat depression?
lactobacillus helveticus
bifidobacterium longum
lactobacillus helveticus
bifidobacterium longum
and here the results were: the probiotics did not help the depression symptoms
why the different results?
placebo effect
the study was done "in association" with the manufacturers of probio'stick?
bottom line: be careful and critical when reading "study results
probiotics promising for mild to moderate depression
probiotics may be effective in reducing core depressive symptoms in treatment-naive patients with a mild to moderate form of the disorder
symptoms of mood, anhedonia, and sleep disturbance were significantly reduced with probiotic therapy after just 4 weeks, with results maintained at 8 weeks
probio'stick, a probiotic supplement that combines two different strains known to act on the gut-brain axis ― lactobacillus helveticus r0052 and bifidobacterium longum r0175
a double-blind, randomized, placebo-controlled trial of lactobacillus helveticus and bifidobacterium longum for the symptoms of depression.
no significant difference was found between the probiotic and placebo groups on any psychological outcome measure or any blood-based biomarker
no evidence that the probiotic formulation is effective in treating low mood, or in moderating the levels of inflammatory and other biomarkers.
frequent consumption of chocolate, cocoa, and cocoa flavanols (an ingredient of cocoa) is linked with beneficial health effects
dose-dependent improvements in cognition, attention, and memory
cocoa and chocolate are not just treats—they are good for your cognition
the cocoa bean is a rich source of flavanols: a class of natural compounds that has neuroprotective effects
what happens to your brain up to a few hours after you eat cocoa flavanols, and what happens when you sustain such a cocoa flavanol enriched diet for a prolonged period of time?
most of them point towards a beneficial effect on cognitive performance
enhancements in working memory performance and improved visual information processing after having had cocoa flavanols
long-term ingestion of cocoa flavanols
in elderly individuals. it turns out that for them cognitive performance was improved by a daily intake of cocoa flavanols
attention, processing speed, working memory, and verbal fluency
cocoa flavanols have beneficial effects for cardiovascular health and can increase cerebral blood volume in the dentate gyrus of the hippocampus
regular intake of cocoa and chocolate could indeed provide beneficial effects on cognitive functioning over time.
skin microbiome
archaea
thaumarchaeota
archaea are more abundant in people older than 60 years or younger than 12 years (as compared to middle-aged persons)
what's on your skin? archaea, that's what
your skin is crawling with single-celled microorganisms
skin microbiome
archaea , a type of extreme-loving microbe, and that the amount of it varies with age
archaea
were most abundant in subjects younger than 12 and older than 60
in addition to the influence of age, they found that gender was not a factor but that people with dry skin have more archaea
cleanup process under dry skin conditions
link lower levels of sebum [the oily secretion of sebaceous glands] and thus reduced skin moisture with an increase of archaeal signatures
the tree of life -- the three branches being bacteria, archaea, and eukarya (which includes all plants and animals). archaea are commonly found in extreme environments
found in the human gut
thaumarchaeota
thaumarchaeota are supposed to be an ammonia-oxidizing microorganism, and ammonia is a major component of sweat, which means they might play a role in nitrogen turnover and skin health
correlated archaeal abundance with skin dryness
 
most archaea are known to be beneficial rather than harmful to human health
b
i
em nanoparticles in foods
titanium dioxide
silicon dioxide
 zinc oxide
titanium dioxide
e171
there may be health effects from the nanoparticles in our food
individuals with inflammatory intestinal conditions such as intestinal bowel disease (colitis and crohn's disease) might have negative health effects 
worsen intestinal inflammation
nanoparticles accumulated in spleens of mice
levels of titanium were increased in the blood of patients with active colitis
titanium dioxide nanoparticles can exacerbate colitis
titanium dioxide
nanoparticles
when intestinal cells absorb titanium dioxide particles, this leads to increased inflammation and damage to the intestinal mucosa in mice with colitis.
patients with colitis should avoid food containing titanium dioxide particles
titanium dioxide nanoparticles can intensify the inflammatory reaction in the bodies of patients with inflammatory intestinal diseases.
no restrictions on its use in the food industry
nlrp3 inflammasome
part of the non-specific immune system, which detects danger signals and then triggers inflammation
nlrp3 can be activated by small inorganic particles
titanium dioxide can penetrate human intestinal epithelial cells and macrophages and accumulate there
patients with ulcerative colitis, whose intestinal barrier is disrupted, have an increased concentration of titanium dioxide in their blood
the particles activated the nlrp3 complex, which led to strong intestinal inflammation and greater damage to the intestinal mucosa in the mice
accumulated in the animals' spleens
based on our results,"
"patients with an intestinal barrier dysfunction as found in colitis should abstain from foods containing titanium dioxide
wallpaper could have fungi (mold) living on it
fungi can release toxins (mycotoxins) that can pollute the air and sicken people when people inhale the toxins
sick building syndrome
why does fungi grow on some wallpaper?
high humidity in the home
water damage
how do the mycotoxins get into the air and move around inside the home?
we normally
breathe in fungi and bacteria
, but inhaling an overload of mycotoxins from moldy wallpaper can sicken a person
fungal toxins from wallpaper source of illness says new research
there are several toxins from fungi that could be released into the air indoors and the source could be fungi living in the wall papers
ordinary fungi that live with the household wallpaper are basically of three types
they can grow and eventually spread to the air
the toxins released from the fungi are called mycotoxins
sick building syndrome
these mycotoxins are released from moldy material of growth of the fungi.
inhaled by the inhabitants of the home
penicillium brevicompactum, aspergillus versicolor and stachybotrys chartarum. a piece of wallpaper was found to be contaminated with these three fungi
on analysis of the indoor air the researchers found that the small particles of dust floating around in the house which could then be inhaled easily, contained toxins from these fungi
phthalates
chemicals used widely in common consumer products
endocrine disruptors
linked to a number of health problems
the higher the level of phthalates, the higher the rate of cardiovascular disease, type-2 diabetes, and hypertension
higher levels of chronic low-grade inflammatory biomarkers
phthalates, which are measured in the urine,  were detected in 99.96% of the 1504 men
everyday chemicals linked to chronic disease in men
chemicals found in everyday plastics materials are linked to cardiovascular disease, type-2 diabetes and high blood pressure in men
association between chronic diseases among men
chemicals known as
phthalates
phthalates
phthalates were detected in urine samples of 99.6% of those aged 35 and ove
prevalence of cardiovascular disease, type-2 diabetes and high blood pressure increased among those men with higher total phthalate levels
the chemicals impact on the human endocrine system , which controls hormone release that regulate the body's growth, metabolism, and sexual development and function. 
higher phthalate levels were associated with increased levels of a range of inflammatory biomarkers in the body
age and western diets are directly associated with higher concentrations of phthalates
although the studies were conducted in men, the findings are also likely to be relevant to women
  red meat allergies from a lone star tick bite?
eat some red meat (beef, pork, or venison) and a few hours later have severe allergy symptoms
lone star tick
alpha-gal allergy syndrome 
alpha-gal
oh, lovely: the tick that gives people meat allergies is spreading
in the last decade and a half, thousands of previously protein-loving americans have developed a dangerous allergy to meat.
the lone star tick
red meat
galactose-alpha-1,3-galactose, or alpha-gal
suddenly develop a life-threatening allergy to that pesky sugar molecule after a tick bite.
, one bite from the lone star tick—which gets its name from the texas-shaped splash of white on its back—is enough to reprogram your immune system to forever reject even the smallest nibble of perfectly crisped bacon
southeastern united states
it’s started to spread
duluth, minnesota, hanover, new hampshire, and the eastern tip of long island
tick bites led to a 20-fold increase in alpha-gal antibodies
something in the tick’s saliva hijacks humans’ immune systems, red-flagging alpha-gal, and triggering the massive release of histamines whenever red meat is consumed
alpha-gal syndrome seems to be the only allergy that affects all people, regardless of genetic makeup.
health benefits associated with drinking coffee daily - this time "reduced risk of death" in 2 studies, and in one study a reduced risk of gallbladder cancer
coffee
both decaffeinated and regular coffee seem beneficial, and it doesn't matter how it is prepared
higher consumption of coffee was associated with a lower risk of death from heart disease, cancer, stroke, diabetes, and kidney disease in african americans, japanese americans, latinos, and whites
coffee drinking was associated with lower risk for death from "all causes", especially from circulatory diseases and diseases related to the digestive tract
the one negative result from drinking more than 3 cups of coffee daily was an increase in risk for ovarian cancer mortality in women
drink coffee? it won’t hurt you, and may reduce your risk of an early death
a couple of massive new studies that looked at hundreds of thousands of people for about 16 years finds that a few cups of coffee a day won’t hurt you and could lower your risk of dying prematurely
521,000 adults from 10 european countries who self-reported their coffee consumption over an average of 16 years
highest 25 percent of coffee consumers had a lower risk of death due to any cause compared to non-coffee drinkers
reduced risk of early death by diseases related to the digestive and circulatory systems
higher coffee consumption and lower risk of early death by lung cancer in men
completed suicides were lower for coffee drinkers, but only in men
180,000 people tracked for an average of 16 years
drinking one to six cups of coffee per week led to a decreased risk of early death
their findings proved consistent for coffee drinkers across racial and ethnic groups
coffee consumption may be linked a lower risk of early death for people with heart disease, cancer, chronic lower respiratory disease, stroke, and kidney disease.
coffee consumption and risk of gallbladder cancer in a prospective study
coffee consumption may reduce the risk of gallstone disease
which is strongly associated with increased risk of gallbladder cancer
coffee consumption was observed to be associated with a reduced risk of gallbladder cancer
  
extra virgin olive oil (evoo)
mediterranean diet
olive oil in the mediterranean diet probably promotes healthy brain aging
they are taking findings from their study done on mice and hypothesizing that this is what is also going on in humans.
enjoy olive oil in your diet - looks like it will benefit your health in a number of ways
olive oil key ingredient in alzheimer's prevention?
extra-virgin olive oil (evoo)
protect memory and learning ability and reduces the formation of beta amyloid (aβ) plaques and neurofibrillary tangles in the brain
it is the olive oil component of the mediterranean diet that likely promotes healthy brain aging
absolutely encourage people to consume greater amounts of evoo
mice fed the evoo-enriched diet performed significantly better at both 9 and 12 months on tests designed to assess working memory, spatial memory, and learning abilities compared with mice fed regular chow
significant reduction in the amount of aβ peptides deposited in the brains of the evoo-treated animals
a significant reduction in the phosphorylated forms of tau in mice fed the evoo-enriched chow
improvements in cognitive performance and brain pathology that were observed in evoo-treated mice
they found greater preservation in the integrity of the synapses between neurons in evoo-fed mice compared with controls
a dramatic increase in nerve cell autophagy activation in brain cells from the evoo-fed animals
autophagy
autophagy digests and gets rid of both amyloid plaques and phosphorylated tau
 
the results of this study done in mice are that actually smelling the food one eats results in weight gain , and not being able to smell the food results in weight loss - even if both groups eat the same amount of food.
supersmellers
 
odor of what we eat
how the body deals with calories
a link between smell and metabolism
smelling your food makes you fat
obese mice who lost their sense of smell also lost weight. 
these slimmed-down but smell-deficient mice ate the same amount of fatty food as mice that retained their sense of smell and ballooned to twice their normal weight
super-smellers—got even fatter on a high-fat diet than did mice with normal smell.
the findings suggest that the odor of what we eat may play an important role in how the body deals with calories
key connection between the olfactory or smell system and regions of the brain that regulate metabolism, in particular the hypothalamus
sensory systems play a role in metabolism
beige fat cells
brown fat cells
some turned almost all of their beige fat into brown fat, becoming lean, mean burning machines
white fat cells
noradrenaline
in humans, such a sustained rise in this hormone could lead to a heart attack
in both cases, the smell-deficient mice ate as much of the high-fat food as did the mice that could still smell.
mice that were already obese lost weight after their smell was knocked out, slimming down to the size of normal mice while still eating a high-fat diet.
supersmellers
they gained more weight on a standard diet than did normal mice
 could probiotics be used to treat depression?
lactobacillus helveticus
bifidobacterium longum
lactobacillus helveticus
bifidobacterium longum
and here the results were: the probiotics did not help the depression symptoms
why the different results?
placebo effect
the study was done "in association" with the manufacturers of probio'stick?
bottom line: be careful and critical when reading "study results
probiotics promising for mild to moderate depression
probiotics may be effective in reducing core depressive symptoms in treatment-naive patients with a mild to moderate form of the disorder
symptoms of mood, anhedonia, and sleep disturbance were significantly reduced with probiotic therapy after just 4 weeks, with results maintained at 8 weeks
probio'stick, a probiotic supplement that combines two different strains known to act on the gut-brain axis ― lactobacillus helveticus r0052 and bifidobacterium longum r0175
a double-blind, randomized, placebo-controlled trial of lactobacillus helveticus and bifidobacterium longum for the symptoms of depression.
no significant difference was found between the probiotic and placebo groups on any psychological outcome measure or any blood-based biomarker
no evidence that the probiotic formulation is effective in treating low mood, or in moderating the levels of inflammatory and other biomarkers.
frequent consumption of chocolate, cocoa, and cocoa flavanols (an ingredient of cocoa) is linked with beneficial health effects
dose-dependent improvements in cognition, attention, and memory
cocoa and chocolate are not just treats—they are good for your cognition
the cocoa bean is a rich source of flavanols: a class of natural compounds that has neuroprotective effects
what happens to your brain up to a few hours after you eat cocoa flavanols, and what happens when you sustain such a cocoa flavanol enriched diet for a prolonged period of time?
most of them point towards a beneficial effect on cognitive performance
enhancements in working memory performance and improved visual information processing after having had cocoa flavanols
long-term ingestion of cocoa flavanols
in elderly individuals. it turns out that for them cognitive performance was improved by a daily intake of cocoa flavanols
attention, processing speed, working memory, and verbal fluency
cocoa flavanols have beneficial effects for cardiovascular health and can increase cerebral blood volume in the dentate gyrus of the hippocampus
regular intake of cocoa and chocolate could indeed provide beneficial effects on cognitive functioning over time.
skin microbiome
archaea
thaumarchaeota
archaea are more abundant in people older than 60 years or younger than 12 years (as compared to middle-aged persons)
what's on your skin? archaea, that's what
your skin is crawling with single-celled microorganisms
skin microbiome
archaea , a type of extreme-loving microbe, and that the amount of it varies with age
archaea
were most abundant in subjects younger than 12 and older than 60
in addition to the influence of age, they found that gender was not a factor but that people with dry skin have more archaea
cleanup process under dry skin conditions
link lower levels of sebum [the oily secretion of sebaceous glands] and thus reduced skin moisture with an increase of archaeal signatures
the tree of life -- the three branches being bacteria, archaea, and eukarya (which includes all plants and animals). archaea are commonly found in extreme environments
found in the human gut
thaumarchaeota
thaumarchaeota are supposed to be an ammonia-oxidizing microorganism, and ammonia is a major component of sweat, which means they might play a role in nitrogen turnover and skin health
correlated archaeal abundance with skin dryness
 
most archaea are known to be beneficial rather than harmful to human health
Bolds strong 197
b 0
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em 197
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lacto bacto http://lactobacto.com/
home http://lactobacto.com/
sinusitis treatment story http://lactobacto.com/our-story/
sinusitis treatment summary http://lactobacto.com/sinusitis-treatment-summary/
about http://lactobacto.com/sample-page/
consultations http://lactobacto.com/consultant/
contact http://lactobacto.com/contact/
donate http://lactobacto.com/donations/
just for fun http://lactobacto.com/just-for-fun/
feeding your gut microbes http://lactobacto.com/feeding-your-gut-microbes/
more concerns with nanoparticles in foods http://lactobacto.com/2017/07/19/more-concerns-with-nanoparticles-in-foods/
http://lactobacto.com/2017/07/19/more-concerns-with-nanoparticles-in-foods/#respond
sima http://lactobacto.com/author/sima/
http://lactobacto.com/2017/07/19/more-concerns-with-nanoparticles-in-foods/
listed on the label https://www.ncbi.nlm.nih.gov/pmc/articles/pmc3288463/#sd1
here http://lactobacto.com/2017/03/23/what-are-the-effects-of-eating-nanoparticles-in-our-food/
here http://lactobacto.com/2016/07/22/are-foods-containing-nanoparticles-safe-to-eat/
a new study http://gut.bmj.com/content/66/7/1216
titanium dioxide nanoparticles can exacerbate colitis https://www.sciencedaily.com/releases/2017/07/170719100521.htm
original study. http://gut.bmj.com/content/66/7/1216
nutrition http://lactobacto.com/category/nutrition/
uncategorized http://lactobacto.com/category/uncategorized/
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nanoparticles http://lactobacto.com/tag/nanoparticles/
titanium dioxide http://lactobacto.com/tag/titanium-dioxide/
http://lactobacto.com/2017/07/19/more-concerns-with-nanoparticles-in-foods/
sima http://lactobacto.com/author/sima/
are fungi growing on your wallpaper? http://lactobacto.com/2017/07/18/are-fungi-growing-on-your-wallpaper/
http://lactobacto.com/2017/07/18/are-fungi-growing-on-your-wallpaper/#respond
sima http://lactobacto.com/author/sima/
http://lactobacto.com/2017/07/18/are-fungi-growing-on-your-wallpaper/
breathe in fungi and bacteria http://lactobacto.com/2015/04/30/we-breathe-in-bacteria-and-fungi-every-day/
fungal toxins from wallpaper source of illness says new research http://www.news-medical.net/news/20170625/fungal-toxins-from-wallpaper-source-of-illness-says-new-research.aspx
new study http://aem.asm.org/content/early/2017/06/05/aem.01001-17
healthy living http://lactobacto.com/category/healthy-living/
microbes http://lactobacto.com/category/microbes/
fungi http://lactobacto.com/tag/fungi/
mold http://lactobacto.com/tag/mold/
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sick building syndrome http://lactobacto.com/tag/sick-building-syndrome/
wallpaper http://lactobacto.com/tag/wallpaper/
http://lactobacto.com/2017/07/18/are-fungi-growing-on-your-wallpaper/
sima http://lactobacto.com/author/sima/
common chemicals linked to chronic diseases http://lactobacto.com/2017/07/14/common-chemicals-linked-to-chronic-diseases/
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http://lactobacto.com/2017/07/14/common-chemicals-linked-to-chronic-diseases/
here http://lactobacto.com/2016/01/04/phthalates-sperm-and-miscarriages/
here http://lactobacto.com/2015/02/20/boys-phthalates-and-later-fertility-problems/
here http://lactobacto.com/2016/10/21/exposure-to-common-chemicals-costs-the-us-340-billion-each-year/
fast food http://lactobacto.com/2016/04/13/fast-food-and-exposure-to-phthalates-and-bpa/
everyday chemicals linked to chronic disease in men https://www.sciencedaily.com/releases/2017/07/170712084807.htm
original study http://www.sciencedirect.com/science/article/pii/s0013935117301330?via%3dihub
cardiovascular health http://lactobacto.com/category/cardiovascular-health/
diabetes http://lactobacto.com/category/diabetes/
endocrine disruptors http://lactobacto.com/category/endocrine-disruptors/
nutrition http://lactobacto.com/category/nutrition/
high blood pressure http://lactobacto.com/tag/high-blood-pressure/
inflammatory biomarkers http://lactobacto.com/tag/inflammatory-biomarkers/
phthalates http://lactobacto.com/tag/phthalates/
http://lactobacto.com/2017/07/14/common-chemicals-linked-to-chronic-diseases/
sima http://lactobacto.com/author/sima/
red meat allergies from a tick bite? http://lactobacto.com/2017/07/13/red-meat-allergies-from-a-tick-bite/
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http://lactobacto.com/2017/07/13/red-meat-allergies-from-a-tick-bite/
science daily https://www.sciencedaily.com/releases/2014/02/140220102727.htm
oh, lovely: the tick that gives people meat allergies is spreading https://www.wired.com/story/lone-star-tick-that-gives-people-meat-allergies-may-be-spreading?mbid=synd_digg
reported being bitten by a tick http://www.jacionline.org/article/s0091-6749%2808%2901931-3/fulltext
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red meat allergy http://lactobacto.com/tag/red-meat-allergy/
http://lactobacto.com/2017/07/13/red-meat-allergies-from-a-tick-bite/
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drinking coffee may reduce risk of death http://lactobacto.com/2017/07/12/drinking-coffee-may-reduce-risk-of-death-2/
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http://lactobacto.com/2017/07/12/drinking-coffee-may-reduce-risk-of-death-2/
here http://lactobacto.com/2016/10/06/drinking-coffee-linked-to-a-reduced-risk-of-dementia/
here http://lactobacto.com/2016/04/08/coffee-colorectal-cancer-and-miscarriage/
here http://lactobacto.com/2015/11/17/drink-coffee-and-live-longer/
one study http://annals.org/aim/article/2643433/association-coffee-consumption-total-cause-specific-mortality-among-nonwhite-populations
other study http://annals.org/aim/article/2643435/coffee-drinking-mortality-10-european-countries-multinational-cohort-study
drink coffee? it won’t hurt you, and may reduce your risk of an early death https://www.statnews.com/2017/07/10/coffee-reduce-early-death/
previous findings https://www.statnews.com/2015/11/16/coffee-extend-life/
[original study http://annals.org/aim/article/2643435/coffee-drinking-mortality-10-european-countries-multinational-cohort-study
original study http://annals.org/aim/article/2643433/association-coffee-consumption-total-cause-specific-mortality-among-nonwhite-populations
coffee consumption and risk of gallbladder cancer in a prospective study http://www.medscape.com/viewarticle/880668
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gallbladder cancer http://lactobacto.com/tag/gallbladder-cancer/
http://lactobacto.com/2017/07/12/drinking-coffee-may-reduce-risk-of-death-2/
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is olive oil good for the aging brain? http://lactobacto.com/2017/07/11/is-olive-oil-good-for-the-aging-brain/
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http://lactobacto.com/2017/07/11/is-olive-oil-good-for-the-aging-brain/
here http://lactobacto.com/2015/09/15/olive-oil-mediterranean-diet-and-breast-cancer/
here http://lactobacto.com/2015/09/10/foods-with-luteolin-and-oleocanthal-are-beneficial/
here http://lactobacto.com/2017/03/08/mediterranean-diet-and-breast-cancer/
olive oil key ingredient in alzheimer's prevention? http://www.medscape.com/viewarticle/882149
brain http://lactobacto.com/category/brain/
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alzheimer's disease (ad) http://lactobacto.com/tag/alzheimers-disease-ad/
extra virgin olive oil (evoo) http://lactobacto.com/tag/extra-virgin-olive-oil-evoo/
http://lactobacto.com/2017/07/11/is-olive-oil-good-for-the-aging-brain/
sima http://lactobacto.com/author/sima/
lose weight if you can’t smell your food? http://lactobacto.com/2017/07/06/lose-weight-if-you-cant-smell-your-food/
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http://lactobacto.com/2017/07/06/lose-weight-if-you-cant-smell-your-food/
the study http://www.cell.com/cell-metabolism/fulltext/s1550-4131(17)30357-1?_returnurl=http%3a%2f%2flinkinghub.elsevier.com%2fretrieve%2fpii%2fs1550413117303571%3fshowall%3dtrue
smelling your food makes you fat https://medicalxpress.com/news/2017-07-mice-lacking-thin.html
original study http://www.cell.com/cell-metabolism/fulltext/s1550-4131(17)30357-1?_returnurl=http%3a%2f%2flinkinghub.elsevier.com%2fretrieve%2fpii%2fs1550413117303571%3fshowall%3dtrue
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super-smellers http://lactobacto.com/tag/super-smellers/
weight gain http://lactobacto.com/tag/weight-gain/
http://lactobacto.com/2017/07/06/lose-weight-if-you-cant-smell-your-food/
sima http://lactobacto.com/author/sima/
do probiotics treat depression or not? http://lactobacto.com/2017/07/05/do-probiotics-treat-depression-or-not/
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sima http://lactobacto.com/author/sima/
http://lactobacto.com/2017/07/05/do-probiotics-treat-depression-or-not/
here http://lactobacto.com/2014/07/10/probiotics-and-psychobiotics-part-1/
here http://lactobacto.com/2014/07/11/probiotics-and-psychobiotics-part-2/
probiotics promising for mild to moderate depression http://www.medscape.com/viewarticle/881877
a double-blind, randomized, placebo-controlled trial of lactobacillus helveticus and bifidobacterium longum for the symptoms of depression. https://www.ncbi.nlm.nih.gov/pubmed/28068788
brain http://lactobacto.com/category/brain/
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http://lactobacto.com/2017/07/05/do-probiotics-treat-depression-or-not/
sima http://lactobacto.com/author/sima/
did you have some chocolate today? http://lactobacto.com/2017/07/03/did-you-have-some-chocolate-today/
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http://lactobacto.com/2017/07/03/did-you-have-some-chocolate-today/
study http://journal.frontiersin.org/article/10.3389/fnut.2017.00019/full
cocoa and chocolate are not just treats—they are good for your cognition https://medicalxpress.com/news/2017-06-cocoa-chocolate-treatsthey-good-cognition.html
original study http://journal.frontiersin.org/article/10.3389/fnut.2017.00019/full
brain http://lactobacto.com/category/brain/
cardiovascular health http://lactobacto.com/category/cardiovascular-health/
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http://lactobacto.com/2017/07/03/did-you-have-some-chocolate-today/
sima http://lactobacto.com/author/sima/
it is normal to have archaea on our skin http://lactobacto.com/2017/06/30/it-is-normal-to-have-archaea-on-our-skin/
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sima http://lactobacto.com/author/sima/
http://lactobacto.com/2017/06/30/it-is-normal-to-have-archaea-on-our-skin/
what's on your skin? archaea, that's what https://www.sciencedaily.com/releases/2017/06/170628172149.htm
original study. https://www.nature.com/articles/s41598-017-04197-4#moesm2
human microbiome http://lactobacto.com/category/human-microbiome/
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http://lactobacto.com/2017/06/30/it-is-normal-to-have-archaea-on-our-skin/
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advanced features of this website require that you enable javascript in your browser. thank you! lacto bacto health, microbes, and more menu skip to content home sinusitis treatment story sinusitis treatment summary about consultations contact donate just for fun feeding your gut microbes more concerns with nanoparticles in foods sima • july 19, 2017  the use of nanoparticles in foods is increasing every year, but we still know very little about whether they have health risks to humans, especially if one is eating foods with them daily (thus having chronic exposure). the nanoparticles in foods are ingredients so small that they are measured in nanometers or billionths of one meter. the most common nanoingredients are: titanium dioxide, silicon dioxide, and zinc oxide. titanium dioxide is typically used as a "food coloring" to make foods whiter or brighter, but it may or may not be listed on the label. in europe, this food additive is known as e171. currently there are no restrictions on using titanium diaoxide nanoparticles in food. recent search suggests that there may be health effects from the nanoparticles in our food (here and here), thus we should be cautious. evidence is accumulating that titanium dioxide nanoparticles can have a negative inflammatory effect on the intestinal lining. similarly, a new study  looking at both mice and humans suggests that individuals with inflammatory intestinal conditions such as intestinal bowel disease (colitis and crohn's disease) might have negative health effects from titanium dioxide nanoparticles - that they could worsen intestinal inflammation. interestingly, the nanoparticles accumulated in spleens of mice used in the study. the researchers also found that levels of titanium were increased in the blood of patients with active colitis. from science daily: titanium dioxide nanoparticles can exacerbate colitis titanium dioxide, one of the most-produced nanoparticles worldwide, is being used increasingly in foodstuffs. when intestinal cells absorb titanium dioxide particles, this leads to increased inflammation and damage to the intestinal mucosa in mice with colitis. researchers at the university of zurich recommend that patients with colitis should avoid food containing titanium dioxide particles. the frequency of inflammatory bowel disease like crohn's disease and ulcerative colitis has been on the rise in many western countries for decades.... in addition to genetic factors, environmental factors like the western lifestyle, especially nutrition, play an essential role in the development of these chronic intestinal diseases. the research of gerhard rogler, professor of gastroenterology and hepatology at the university of zurich, now shows that titanium dioxide nanoparticles can intensify the inflammatory reaction in the bodies of patients with inflammatory intestinal diseases. titanium dioxide is a white pigment used in medicines, cosmetics and toothpaste and increasingly as food additive e171, for example, in icing, chewing gum or marshmallows. until now, there have been no restrictions on its use in the food industry. the scientists led by gerhard rogler concentrated their research on a protein complex inside cells: the nlrp3 inflammasome. this protein complex is part of the non-specific immune system, which detects danger signals and then triggers inflammation. if the inflammasome is activated by bacterial components, for example, and the inflammatory reaction plays a vital role in the defense against infective agents. in the same way, nlrp3 can be activated by small inorganic particles -- sometimes with negative consequences: if uric acid crystals form in the cells, for example the inflammation leads to gout. the research team first studied the effect of inorganic titanium dioxide particles in cell cultures. they were able to show that titanium dioxide can penetrate human intestinal epithelial cells and macrophages and accumulate there. the nanoparticles were detected as danger signals by inflammasomes, which triggered the production of inflammatory messengers. in addition, patients with ulcerative colitis, whose intestinal barrier is disrupted, have an increased concentration of titanium dioxide in their blood. "this shows that these particles can be absorbed from food under certain disease conditions," rogler says. in a further step, the scientists orally administered titanium dioxide nanoparticles to mice, which serve as a disease model for inflammatory bowel disease. here, as well, the particles activated the nlrp3 complex, which led to strong intestinal inflammation and greater damage to the intestinal mucosa in the mice. in addition, titanium dioxide crystals accumulated in the animals' spleens. whether these findings will be confirmed in humans must now be determined in further studies. "based on our results," rogler concludes, "patients with an intestinal barrier dysfunction as found in colitis should abstain from foods containing titanium dioxide."  [original study.] posted in nutrition, uncategorized. tags: colitis, crohn's disease, intestinal bowel disease (ibd), nanoparticles, titanium dioxide on july 19, 2017 by sima. are fungi growing on your wallpaper? sima • july 18, 2017  how many people know this? that wallpaper could have fungi (mold) living on it, and this fungi can release toxins (mycotoxins) that can pollute the air and sicken people when people inhale the toxins. the releasing of toxins from the fungi (mold) into the air is called aerosolization - and when this indoor air pollution causes people  living or working in the building to become sick, it is called sick building syndrome. this study looked at 3 common indoor fungal species: penicillium brevicompactum, aspergillus versicolor, and stachybotrys chartarum, and the mycotoxins they produce after growing on wallpaper. why does fungi grow on some wallpaper?  the researchers write that: "many fungi can develop on building material in indoor environments if moisture is high enough". so either high humidity in the home (especially when the weather is hot) or water damage can result in mold growth. it is estimated that in northern europe and north america about 20 to 40 % of buildings have visible fungal growth on surfaces. how do the mycotoxins get into the air and move around inside the home? ordinary living, with people moving around rooms, slamming doors, air drafts from opening windows, and ceiling fans all cause "air velocities" that move around the toxins. please note that we normally breathe in fungi and bacteria, but inhaling an overload of mycotoxins from moldy wallpaper can sicken a person. from news-medical: fungal toxins from wallpaper source of illness says new research according to a new study, there are several toxins from fungi that could be released into the air indoors and the source could be fungi living in the wall papers. these may lead to serious health problems say researchers. these ordinary fungi that live with the household wallpaper are basically of three types found the study researchers. they can grow and eventually spread to the air. this leads to serious health consequences. these effects of transmission of the airborne fungi and their toxins on human health have not been studied or considered with importance till date say researchers. the toxins released from the fungi are called mycotoxins. they can pollute the indoor air and lead to indoor air pollution – a condition called sick building syndrome. sick building syndrome is a condition where the residents start to feel ill according to the time they have spent in a building.... study co-author jean-denis bailly, a professor of food hygiene at the national veterinary school of toulouse in france in a statement explained that these mycotoxins are released from moldy material of growth of the fungi. they are eventually inhaled by the inhabitants of the home. while investigating the quality of air indoors especially at homes that have higher fungal contamination, the indoor air quality also needs to be tested for fungal toxins, he explained. according to researchers, there has been extensive study of fungal contamination of food. however there has been little work in terms of fungal toxins in air. for this study they looked at three fungi that commonly also contaminated foods - penicillium brevicompactum, aspergillus versicolor and stachybotrys chartarum. a piece of wallpaper was found to be contaminated with these three fungi. a flowing stream of air was allowed over the wallpaper and samples of air of the room were then collected for testing. on analysis of the indoor air the researchers found that the small particles of dust floating around in the house which could then be inhaled easily, contained toxins from these fungi. also all fungi did not spread the toxins at the same rates they found. some spread more toxins than others and this could help researchers to decide on which fungi species to concentrate on in terms of disease prevention they said. posted in healthy living, microbes. tags: fungi, mold, mycotoxins, sick building syndrome, wallpaper on july 18, 2017 by sima. common chemicals linked to chronic diseases sima • july 14, 2017  another study was just published with worrisome findings about phthalates. phthalates are a group of chemicals used widely in common consumer products such as food packaging, toys, medical devices, medications, and personal care products. they are endocrine disruptors (can interfere with normal hormonal function) and are linked to a number of health problems (here, here, and here). the study looked at urban australian men and found that the higher the level of phthalates, the higher the rate of cardiovascular disease, type-2 diabetes, and hypertension. the researchers also found that higher levels of chronic low-grade inflammatory biomarkers (meaning higher levels of low-grade inflammation) was associated with higher levels of phthalates. all these findings confirm what other studies, done in other countries, have found. phthalates, which are measured in the urine,  were detected in 99.96% of the 1504 men. eating a western dietary pattern (fast food, highly processed, low fiber) was also associated with higher phthalate levels.  however, they did not find an association of phthalate levels with asthma and depression. from science daily: everyday chemicals linked to chronic disease in men chemicals found in everyday plastics materials are linked to cardiovascular disease, type-2 diabetes and high blood pressure in men, according to australian researchers. researchers from the university of adelaide and the south australian health and medical research institute (sahmri) investigated the independent association between chronic diseases among men and concentrations of potentially harmful chemicals known as phthalates. phthalates are a group of chemicals widely used in common consumer products, such as food packaging and wrappings, toys, medications, and even medical devices. researchers found that of the 1500 australian men tested, phthalates were detected in urine samples of 99.6% of those aged 35 and over. "we found that the prevalence of cardiovascular disease, type-2 diabetes and high blood pressure increased among those men with higher total phthalate levels," says senior author associate professor zumin shi, from the university of adelaide's adelaide medical school and the freemasons foundation centre for men's health, and a member of sahmri's nutrition & metabolism theme. "while we still don't understand the exact reasons why phthalates are independently linked to disease, we do know the chemicals impact on the human endocrine system, which controls hormone release that regulate the body's growth, metabolism, and sexual development and function. "in addition to chronic diseases, higher phthalate levels were associated with increased levels of a range of inflammatory biomarkers in the body," he says. age and western diets are directly associated with higher concentrations of phthalates. previous studies have shown that men who ate less fresh fruit and vegetables and more processed and packaged foods, and drank carbonated soft drinks, have higher levels of phthalates in their urine.... associate professor shi says that although the studies were conducted in men, the findings are also likely to be relevant to women. "while further research is required, reducing environmental phthalates exposure where possible, along with the adoption of healthier lifestyles, may help to reduce the risk of chronic disease," he says. [original study.] posted in cardiovascular health, diabetes, endocrine disruptors, nutrition. tags: high blood pressure, inflammatory biomarkers, phthalates on july 14, 2017 by sima. red meat allergies from a tick bite? sima • july 13, 2017   red meat allergies from a lone star tick bite? i first read about this a few years ago in science daily and it seemed pretty incredible - eat some red meat (beef, pork, or venison) and a few hours later have severe allergy symptoms such as itching, hives, swelling, shortness of breath, vomiting, and diarrhea. and the allergy starts after a person is bitten by a lone star tick. a few years ago the red meat allergy seemed to occur only in the southeastern united states. but recently the severe red meat allergies are occurring in new places (such as minnesota and long island, ny) - so it appears that either the area where this tick lives is spreading or other species of ticks are also now causing this allergy. by the way, once a person has this allergy there is no cure, vaccine, or treatment other than avoiding red meat, treating the allergy symptoms, and carrying an epipen (just in case). it is also referred to as alpha-gal allergy syndrome because the allergy is to the sugar molecule commonly called alpha-gal which is found in red meat and some medications (such as the cancer drug cetuximab). from wired: oh, lovely: the tick that gives people meat allergies is spreading first comes the unscratchable itching, and the angry blossoming of hives. then stomach cramping, and—for the unluckiest few—difficulty breathing, passing out, and even death. in the last decade and a half, thousands of previously protein-loving americans have developed a dangerous allergy to meat. and they all have one thing in common: the lone star tick. red meat, you might be surprised to know, isn’t totally sugar-free. it contains a few protein-linked saccharides, including one called galactose-alpha-1,3-galactose, or alpha-gal, for short. more and more people are learning this the hard way, when they suddenly develop a life-threatening allergy to that pesky sugar molecule after a tick bite. yep, one bite from the lone star tick—which gets its name from the texas-shaped splash of white on its back—is enough to reprogram your immune system to forever reject even the smallest nibble of perfectly crisped bacon. for years, physicians and researchers only reported the allergy in places the lone star tick calls home, namely the southeastern united states. but recently it’s started to spread. the newest hot spots? duluth, minnesota, hanover, new hampshire, and the eastern tip of long island, where at least 100 cases have been reported in the last year. scientists are racing to trace its spread, to understand if the lone star tick is expanding into new territories, or if other species of ticks are now causing the allergy. over the next few years platts-mills and his colleague scott commins screened more meat allergy patients and discovered that 80 percent reported being bitten by a tick.what’s more, they showed that tick bites led to a 20-fold increase in alpha-gal antibodies. since ethics standards prevented them from attaching ticks to randomized groups of patients, this data was the best they could do to guess how meat allergy arises. something in the tick’s saliva hijacks humans’ immune systems, red-flagging alpha-gal, and triggering the massive release of histamines whenever red meat is consumed.researchers are still trying to find what that something is.  whatever it is, allergy researchers will be paying attention. because, as far as anyone can tell, alpha-gal syndrome seems to be the only allergy that affects all people, regardless of genetic makeup. “there’s something really special about this tick,” says jeff wilson, an asthma, allergy, and immunology fellow in platts-mills’ group. usually a mix of genes and environmental factors combine to create allergies. but when it comes to the lone star tick it doesn’t matter if you’re predisposed or not. “just a few bites and you can render anyone really, really allergic,” he says.  lone star tick credit: cdc public image library posted in uncategorized. tags: alpha-gal, alpha-gal allergy syndrome, lone star tick, red meat allergy on july 13, 2017 by sima. drinking coffee may reduce risk of death sima • july 12, 2017  once again several studies found health benefits associated with drinking coffee daily - this time "reduced risk of death" in 2 studies, and in one study a reduced risk of gallbladder cancer. just keep in mind that the studies found associations, but did not establish that drinking coffee caused x (reduced risk of death) - so perhaps coffee drinkers differ in some still unknown way from non-coffee drinkers. but...so many studies are piling up showing an association with health benefits that it looks likely that it is actually the coffee causing the benefits. both decaffeinated and regular coffee seem beneficial, and it doesn't matter how it is prepared (e.g., espresso, drip, cappuccino). (earlier posts about coffee - here, here, here) in the one study higher consumption of coffee was associated with a lower risk of death from heart disease, cancer, stroke, diabetes, and kidney disease in african americans, japanese americans, latinos, and whites. people who consumed a cup of coffee a day (decaffeinated or regular) were 12 percent less likely to die compared to those who didn't drink coffee, and those who drank two to three cups a day had an 18 percent reduced chance of death. the conclusion of the other study of over half million adults in 10 european countries was similar: coffee drinking was associated with lower risk for death from "all causes", especially from circulatory diseases and diseases related to the digestive tract. this association held up among all the countries. the highest levels of consumption  group (3 cups or more of coffee per day)  had the lowest risk of death - as compared to those drinking none or less than 1 cup of coffee per day. however, the one negative result from drinking more than 3 cups of coffee daily was an increase in risk for ovarian cancer mortality in women (but only when compared to coffee non-drinkers). from stat news: drink coffee? it won’t hurt you, and may reduce your risk of an early death good news, coffee drinkers: a couple of massive new studies that looked at hundreds of thousands of people for about 16 years finds that a few cups of coffee a day won’t hurt you and could lower your risk of dying prematurely. the studies reinforce previous findings that drinking an 8-ounce cup of joe (or three) won’t hurt you, but the authors of the new works and other experts say caveats abound. murphy told stat his is the largest study on coffee and mortality to date. in the study, researchers with the who’s international agency for research on cancer and imperial college london tracked 521,000 adults from 10 european countries who self-reported their coffee consumption over an average of 16 years.... in investigating more than 40,000 deaths from this group, the team found that participants who fell into the highest 25 percent of coffee consumers had a lower risk of death due to any cause compared to non-coffee drinkers. they saw a reduced risk of early death by diseases related to the digestive and circulatory systems. the researchers also discovered a link between higher coffee consumption and lower risk of early death by lung cancer in men. and they also looked at suicide — completed suicides were lower for coffee drinkers, but only in men. [original study.] in a second study of 180,000 people tracked for an average of 16 years, university of southern california investigators found drinking one to six cups of coffee per week led to a decreased risk of early death. the study was focused on non-white populations, andtheir findings proved consistent for coffee drinkers across racial and ethnic groups. one of the usc study’s senior authors, v. wendy setiawan... said coffee consumption may be linked a lower risk of early death for people with heart disease, cancer, chronic lower respiratory disease, stroke, and kidney disease.drink one cup per day, and the risk of dying early from those diseases decreases by 12 percent, she said. [original study.] this 2016 study is from medscape: coffee consumption and risk of gallbladder cancer in a prospective study evidence indicates that coffee consumption may reduce the risk of gallstone disease, which is strongly associated with increased risk of gallbladder cancer. the association between coffee consumption and gallbladder cancer incidence was examined in a prospective cohort study of 72,680 swedish adults (aged 45 − 83 years) who were free of cancer and reported their coffee consumption at baseline.....  in conclusion, coffee consumption was observed to be associated with a reduced risk of gallbladder cancer. a potential protective association between coffee consumption and risk of gallbladder cancer may be mediated via reduced gallstone formation or through other mechanisms such as reduction of oxidative damage and inflammation and regulation of dna repair, phase ii enzymatic activity, apoptosis, angiogenesis, and metastasis. posted in cancer, cardiovascular health, healthy aging, healthy living, nutrition. tags: coffee, gallbladder cancer on july 12, 2017 by sima. is olive oil good for the aging brain? sima • july 11, 2017   lately more and more research has been finding health benefits with frequent consumption of extra virgin olive oil (evoo). it is also a basic part of the popular mediterranean diet - which emphasizes fresh fruits and vegetables, nuts, legumes (beans), whole grains, some fish, and extra virgin olive oil. now a study conducted by investigators at temple university in philadelphia, pennsylvania, suggests that the olive oil in the mediterranean diet probably promotes healthy brain aging. the researchers said: "our study is the first demonstration that evoo can beneficially affect memory, amyloid plaques, and tau pathology, the hallmark lesions in the brain of alzheimer's patients." but... note that they are taking findings from their study done on mice and hypothesizing that this is what is also going on in humans.  their study used specially bred mice (and only 22 in total) - one group which received extra virgin olive oil in their food (starting at 6 months of age), and the other not. the researchers found that after a few months of this diet that there were differences between the 2 groups when tested at 12 months (which is also when they were euthanized). note that mice are short lived and after 6 months they are considered "mature adults". the researchgers now plan to test varying daily doses of evoo on humans soon - this way they can see what the minimal dosage is for beneficial effects (if any), and if there is a maximal dosage where there are negative health effects. in the meantime, enjoy olive oil in your diet - looks like it will benefit your health in a number of ways (here, here, and here). from medscape: olive oil key ingredient in alzheimer's prevention? extra-virgin olive oil (evoo) appears to protect memory and learning ability and reduces the formation of beta amyloid (aβ) plaques and neurofibrillary tangles in the brain — the classic hallmarks of alzheimer's disease (ad) — new animal research shows. the study, conducted by investigators at temple university in philadelphia, pennsylvania, suggests that it is the olive oil component of the mediterranean diet that likely promotes healthy brain aging.... "and results are important enough to absolutely encourage people to consume greater amounts of evoo. given that it's been consumed for at least 2000 years, i do not anticipate any side effects," he added. for the study, the investigators tested the potentially beneficial effects of evoo on triple transgenic mice. these mice are specifically bred to develop key pathologic features of ad (alzheimer's disese), including amyloid plaques and neurofibrillary tangles. the animals were divided into two groups. one group received evoo-enriched chow, and the other received regular chow without evoo. the olive oil was introduced into the diet when the mice were 6 months of age, before they began to develop symptoms of ad..... the mice were subjected to the same behavioral tests at both 9 and 12 months of age, after which they were euthanized and their brains were examined for the presence of key pathologic features of ad. the researchers confirmed that mice fed the evoo-enriched diet performed significantly better at both 9 and 12 months on tests designed to assess working memory, spatial memory, and learning abilities compared with mice fed regular chow. the researchers also found a statistically significant reduction in the amount of aβ peptides deposited in the brains of the evoo-treated animals compared with controls. there was also a significant reduction in the phosphorylated forms of tau in mice fed the evoo-enriched chow compared to controls, although olive oil had no effect on total tau levels in the same region of the brain. the investigators also examined whether the improvements in cognitive performance and brain pathology that were observed in evoo-treated mice might be the result of an improvement in synaptic integrity. once again, they found greater preservation in the integrity of the synapses between neurons in evoo-fed mice compared with controls....  furthermore, there was a dramatic increase in nerve cell autophagy activation in brain cells from the evoo-fed animals compared with controls. dr pratico explained that autophagy is a mechanism by which cells digest proteins that are produced in excess or that are abnormal. in this particular animal model, autophagy digests and gets rid of both amyloid plaques and phosphorylated tau. "thanks to the autophagy activation, memory and synaptic integrity were preserved, and the pathological effects in animals otherwise destined to develop alzheimer's disease were significantly reduced. this is a very important discovery, since we suspect that a reduction in autophagy marks the beginning of alzheimer's disease." posted in brain, healthy aging, healthy living, nutrition. tags: alzheimer's disease (ad), extra virgin olive oil (evoo) on july 11, 2017 by sima. lose weight if you can’t smell your food? sima • july 6, 2017  the following is a study with weird results, really weird results. and it makes me think of all the times i've heard people joke: "just smelling food makes me gain weight", because we all knew it wasn't true. but what if it was true? .... the results of this study done in mice are that actually smelling the food one eats results in weight gain, and not being able to smell the food results in weight loss - even if both groups eat the same amount of food. and the "supersmellers" (those with a "boosted" sense of smell) gained the most weight of all. what? how could that be? yes, the study was done in mice, but perhaps it also applies to humans (the researchers think so). the researchers think  that the odor of what we eat may play an important role in how the body deals with calories - if you can't smell your food, you may burn it rather than store it. in other words, a link between smell and metabolism. excerpts from science daily: smelling your food makes you fat our sense of smell is key to the enjoyment of food, so it may be no surprise that in experiments at the university of california, berkeley, obese mice who lost their sense of smell also lost weight. what's weird, however, is that these slimmed-down but smell-deficient mice ate the same amount of fatty food as mice that retained their sense of smell and ballooned to twice their normal weight. in addition, mice with a boosted sense of smell—super-smellers—got even fatter on a high-fat diet than did mice with normal smell. the findings suggest that the odor of what we eat may play an important role in how the body deals with calories. if you can't smell your food, you may burn it rather than store it. these results point to a key connection between the olfactory or smell system and regions of the brain that regulate metabolism, in particular the hypothalamus, though the neural circuits are still unknown. the new study, published this week in the journal cell metabolism, implies that the loss of smell itself plays a role, and suggests possible interventions for those who have lost their smell as well as those having trouble losing weight. "sensory systems play a role in metabolism. weight gain isn't purely a measure of the calories taken in; it's also related to how those calories are perceived," said senior author andrew dillin,... the smell-deficient mice rapidly burned calories by up-regulating their sympathetic nervous system, which is known to increase fat burning. the mice turned their beige fat cells—the subcutaneous fat storage cells that accumulate around our thighs and midriffs - into brown fat cells, which burn fatty acids to produce heat. some turned almost all of their beige fat into brown fat, becoming lean, mean burning machines. in these mice, white fat cells—the storage cells that cluster around our internal organs and are associated with poor health outcomes—also shrank in size. the obese mice, which had also developed glucose intolerance - a condition that leads to diabetes—not only lost weight on a high-fat diet, but regained normal glucose tolerance. on the negative side, the loss of smell was accompanied by a large increase in levels of the hormone noradrenaline, which is a stress response tied to the sympathetic nervous system. in humans, such a sustained rise in this hormone could lead to a heart attack. dillin and riera developed two different techniques to temporarily block the sense of smell in adult mice. .... in both cases, the smell-deficient mice ate as much of the high-fat food as did the mice that could still smell. but while the smell-deficient mice gained at most 10 percent more weight, going from 25-30 grams to 33 grams, the normal mice gained about 100 percent of their normal weight, ballooning up to 60 grams. for the former, insulin sensitivity and response to glucose - both of which are disrupted in metabolic disorders like obesity - remained normal. mice that were already obese lost weight after their smell was knocked out, slimming down to the size of normal mice while still eating a high-fat diet. these mice lost only fat weight, with no effect on muscle, organ or bone mass. the uc berkeley researchers then teamed up with colleagues in germany who have a strain of mice that are supersmellers, with more acute olfactory nerves, and discovered that they gained more weight on a standard diet than did normal mice. [original study.] posted in nutrition, uncategorized. tags: calories, sense of smell, super-smellers, weight gain on july 6, 2017 by sima. do probiotics treat depression or not? sima • july 5, 2017  could probiotics be used to treat depression? the medical site medscape reported on a very small preliminary study (only 10 people) that tested that idea, with findings that suggested that taking certain probiotics does help treat the symptoms of mild to moderate depression. the bacteria taken were lactobacillus helveticus and bifidobacterium longum (in the product probio'stick). specifically, the symptoms of mood, anhedonia (inability to feel pleasure), and sleep disturbance were significantly reduced after probiotoc therapy. sounds great, yes? but ....just a few months ago a much larger study was published where people were randomly assigned to either a placebo group or the treatment group (the same 2 probiotics: lactobacillus helveticus and bifidobacterium longum). it was also "double-blind" - so no one knew who got the placebo or the treatment. and here the results were: the probiotics did not help the depression symptoms. this study found "no evidence that the probiotic formulation is effective in treating low mood, or in moderating the levels of inflammatory and other biomarkers". why the different results? maybe the "placebo effect" was why the 10 person study had a positive effect. wanting and thinking something works can definitely influence results. (this is why ideally studies are double-blind, randomized, and with a placebo.) or was it because the study was done "in association" with the manufacturers of probio'stick? yup, it's not surprising the manufacturer of a product finds a "positive effect" from its product. bottom line: be careful and critical when reading "study results". however, after saying all that - there is a "gut-brain axis" in humans, and some researchers are examining whether probiotics can treat various symptoms such as anxiety (here and here). so perhaps some other probiotic bacteria might work to treat depression. the problematic study from medscape: probiotics promising for mild to moderate depression probiotics may be effective in reducing core depressive symptoms in treatment-naive patients with a mild to moderate form of the disorder, results of a new pilot study suggest. investigators led by caroline wallace, phd candidate, queen's university, kingston, ontario, canada, found that symptoms of mood, anhedonia, and sleep disturbance were significantly reduced with probiotic therapy after just 4 weeks, with results maintained at 8 weeks..... the hypothesis is that the effects are mediated via the gut-brain axis by reducing inflammation and increasing serotonin levels. to assess the efficacy of probiotics in treatment-naive patients with depression, the researchers carried out a pilot study using probio'stick, a probiotic supplement that combines two different strains known to act on the gut-brain axis ― lactobacillus helveticus r0052 and bifidobacterium longum r0175. the 8-week, single-arm, open-label intervention pilot study involved 10 treatment-naive patients with major depressive disorder who were experiencing a current episode of depression..... next steps will be to confirm these findings in a double-blind, randomized, placebo-controlled trial of probio'stick.  same probiotic bacteria, but no effect from the treatment. from the australian and new zealand journal of psychiatry: a double-blind, randomized, placebo-controlled trial of lactobacillus helveticus and bifidobacterium longum for the symptoms of depression. no significant difference was found between the probiotic and placebo groups on any psychological outcome measure or any blood-based biomarker. this study found no evidence that the probiotic formulation is effective in treating low mood, or in moderating the levels of inflammatory and other biomarkers. the lack of observed effect on mood symptoms may be due to the severity, chronicity or treatment resistance of the sample; recruiting an antidepressant-naive sample experiencing mild, acute symptoms of low mood, may well yield a different result. future studies taking a preventative approach or using probiotics as an adjuvant treatment may also be more effective. vitamin d levels should be monitored in future studies in the area. the results of this trial are preliminary; future studies in the area should not be discouraged. posted in brain, microbes, probiotics, uncategorized. tags: bifidobacterium longum, depression, lactobacillus helveticus on july 5, 2017 by sima. did you have some chocolate today? sima • july 3, 2017  chocolate lovers can rejoice - because another study, which was actually a review of other studies - found that frequent consumption of chocolate, cocoa, and cocoa flavanols (an ingredient of cocoa) is linked with beneficial health effects. these included cardiovascular benefits, and dose-dependent improvements in cognition, attention, and memory. in other words - the more frequently one eats chocolate and cocoa (especially dark chocolate), the more beneficial health effects. so eat and enjoy! from medical xpress: cocoa and chocolate are not just treats—they are good for your cognition a balanced diet is chocolate in both hands - a phrase commonly used to justify one's chocolate snacking behavior. a phrase now shown to actually harbor some truth, as the cocoa bean is a rich source of flavanols: a class of natural compounds that has neuroprotective effects. in their recent review published in frontiers in nutrition, italian researchers examined the available literature for the effects of acute and chronic administration of cocoa flavanols on different cognitive domains. in other words: what happens to your brain up to a few hours after you eat cocoa flavanols, and what happens when you sustain such a cocoa flavanol enriched diet for a prolonged period of time? although randomized controlled trials investigating the acute effect of cocoa flavanols are sparse, most of them point towards a beneficial effect on cognitive performance. participants showed, among others, enhancements in working memory performance and improved visual information processing after having had cocoa flavanols. and for women, eating cocoa after a night of total sleep deprivation actually counteracted the cognitive impairment (i.e. less accuracy in performing tasks) that such a night brings about. promising results for people that suffer from chronic sleep deprivation or work shifts. the effects of relatively long-term ingestion of cocoa flavanols (ranging from 5 days up to 3 months) has generally been investigated in elderly individuals. it turns out that for them cognitive performance was improved by a daily intake of cocoa flavanols. factors such as attention, processing speed, working memory, and verbal fluency were greatly affected. these effects were, however, most pronounced in older adults with a starting memory decline or other mild cognitive impairments. and this was exactly the most unexpected and promising result according to authors valentina socci and michele ferrara from the university of l'aquila in italy. "this result suggests the potential of cocoa flavanols to protect cognition in vulnerable populations over time by improving cognitive performance. if you look at the underlying mechanism, the cocoa flavanols have beneficial effects for cardiovascular health and can increase cerebral blood volume in the dentate gyrus of the hippocampus. this structure is particularly affected by aging and therefore the potential source of age-related memory decline in humans." so should cocoa become a dietary supplement to improve our cognition? "regular intake of cocoa and chocolate could indeed provide beneficial effects on cognitive functioning over time. there are, however, potential side effects of eating cocoa and chocolate. those are generally linked to the caloric value of chocolate, some inherent chemical compounds of the cocoa plant such as caffeine and theobromine, and a variety of additives we add to chocolate such as sugar or milk." nonetheless, the scientists are the first to put their results into practice: "dark chocolate is a rich source of flavanols. so we always eat some dark chocolate. every day." [original study.] posted in brain, cardiovascular health, healthy aging, nutrition. tags: chocolate, cocoa, flavanols on july 3, 2017 by sima. it is normal to have archaea on our skin sima • june 30, 2017  something new to add to the list of what is in our skin microbiome - the community of microbes (bacteria, fungi, viruses) living on our skin. it turns out we also have archaea, which are single-celled microorganisms that are thought to be beneficial. the human skin microbiome acts as a barrier protecting our body from pathogens and other environmental influences. the most common archaea found in the samples (from the chest area of 51 volunteers between the ages of 1 to 75 years) is called thaumarchaeota. the results reveal that archaea are more abundant in people older than 60 years or younger than 12 years (as compared to middle-aged persons). but there were no differences between males and females. from science daily: what's on your skin? archaea, that's what it turns out your skin is crawling with single-celled microorganisms -- and they're not just bacteria. a study by the department of energy's lawrence berkeley national laboratory (berkeley lab) and the medical university of graz has found that the skin microbiome also contains archaea, a type of extreme-loving microbe, and that the amount of it varies with age. the researchers conducted both genetic and chemical analyses of samples collected from human volunteers ranging in age from 1 to 75. they found that archaea (pronounced ar-key-uh) were most abundant in subjects younger than 12 and older than 60.  in addition to the influence of age, they found that gender was not a factor but that people with dry skin have more archaea. "archaea might be important for the cleanup process under dry skin conditions," said moissl-eichinger. "the results of our genetic analysis (dna-based quantitative pcr and next-generation sequencing), together with results obtained from infrared spectroscopy imaging, allowed us to link lower levels of sebum [the oily secretion of sebaceous glands] and thus reduced skin moisture with an increase of archaeal signatures." it was not until the 1970s that scientists realized how different archaea were from bacteria, and they became a separate branch on the tree of life -- the three branches being bacteria, archaea, and eukarya (which includes all plants and animals). archaea are commonly found in extreme environments, such as hot springs and antarctic ice. nowadays it is known that archaea exist in sediments and in earth's subsurface as well, but they have only recently been found in the human gut and linked with the human microbiome. their study focused on thaumarchaeota, one of the many phyla of archaea, as little evidence of the others was found in the pilot study. "we know that thaumarchaeota are supposed to be an ammonia-oxidizing microorganism, and ammonia is a major component of sweat, which means they might play a role in nitrogen turnover and skin health," holman said. .... the team also correlated archaeal abundance with skin dryness, as middle-aged persons have higher sebum levels and thus moister skin than the elderly. so far, most archaea are known to be beneficial rather than harmful to human health. they may be important for reducing skin ph or keeping it at low levels, and lower ph is associated with lower susceptibility to infections.  [original study.]  thaumarchaeota archaea. these single-celled organisms have just one membrane sac that encloses their bodies. credit: univ. of washington posted in human microbiome, microbes. tags: archaea, skin microbiome, thaumarchaeota on june 30, 2017 by sima. post navigation ← older posts search for: categories blood pressure brain breast cancer cancer cardiovascular health children diabetes endocrine disruptors exercise flame retardants healthy aging healthy living human microbiome lyme disease microbes nutrition pesticides pregnancy and childbirth probiotics sinusitis stroke uncategorized urinary tract infections archives archives select month july 2017 june 2017 may 2017 april 2017 march 2017 february 2017 january 2017 december 2016 november 2016 october 2016 september 2016 august 2016 july 2016 june 2016 may 2016 april 2016 march 2016 february 2016 january 2016 december 2015 november 2015 october 2015 september 2015 august 2015 july 2015 june 2015 may 2015 april 2015 march 2015 february 2015 january 2015 december 2014 november 2014 october 2014 september 2014 august 2014 july 2014 june 2014 may 2014 april 2014 march 2014 february 2014 january 2014 december 2013 © mara silgailis. 2013-2017. all rights reserved. • web development by your credentials • --> log in powered by wordpress


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